We have an exciting opportunity as the Associate Director of Pharmacology for an innovative clinical stage biotech based in Oxford. This is a fantastic role for someone looking for in interesting and challenging role focussed on translational modelling, population PK, PK/PD, exposure-response, disease modelling and simulations across clinical development phases. Responsibilities To lead (on a project level) relevant pharmacometrics analysis such as non-compartmental PK, PK/PD, population PK and PK/PD, exposure-response, modelling and simulation methods, meta-analyses, disease and systems biology modelling Implement innovative analytical methods in pharmacometrics and modelling and simulation in order to integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics and disease states in support of optimal dosing designs Lead non-compartmental PK analyses, build NONMEM datasets, generate report tables, figures, and listings from NCA or popPK analyses for regulatory submissions, and maintain regulatory documentation Provide pharmacometrics contributions to regulatory documents including Clinical Study Reports, Investigator Brochures and those required for regulatory submissions and follow-up responses Identify and implement all necessary hardware and software systems, together with relevant quality processes, for the conduct of in-house pharmacometrics activities Provide modelling and simulation support to Research and TransMed teams for the investigation of exposure-driven functional studies to elucidate mechanism of action and platform development Advise pre-clinical teams on animal model PK/PD, receptor occupancy and translate insights to predict doses for clinical investigation Collaborate with Clinical Pharmacology consultants and academics Requirements Prior experience in pharmacometrics and advanced modelling and simulation Significant expertise within the field of M&S, including PK, PKPD and statistics. Strong knowledge of pharmacokinetics and exposure-response analysis Translational and clinical development experience with an emphasis on pharmacometrics Ability to identify, develop execute strategic modelling and simulation strategies at the project level. Training and experience with PK and statistical software Following your application Simon Trebilcock, a specialist Scientific Recruiter with over 8 years' experience recruiting in the field will discuss the opportunity with you in detail. He will be more than happy to answer any questions relating to the pharmaceutical industry and the potential for your career growth. The conversation can also progress further to discussing other opportunities which are also available right now or will be imminently becoming available. This position has been highly popular, and it is likely that it will close prematurely. We recommend applying as soon as possible to avoid disappointment. Please click 'apply' or contact Simon Trebilcock for any further information Email - Telephone - (0) . A note from the author - Simon Trebilcock Don't meet every single requirement? Studies have shown that women and people from minority groups are less likely to apply to job adverts unless they meet every single qualification. At Planet Pharma we are dedicated to building diverse, inclusive and authentic workplaces, so if you're excited about this role but your past experience doesn't align perfectly with every qualification in the advert, we encourage you to apply anyway. You may be just the right candidate for this or other roles.